The Mlx Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The Mlx Antibody has been validated for the following applications: Western Blot.
Description
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.Billin A.N., J. Biol. Chem. 274:36344-36350(1999).Meroni G., Oncogene 19:3266-3277(2000).Ota T., Nat. Genet. 36:40-45(2004)